Endocrine Abstracts

A 34-year-old T1DM nurse was admitted with a history of recurrent episodes of DKA. In the current admission at our hospital, on detailed history she reported of getting DKA almost every month when her menses would start. She would be following the sick day rules of DKA but it wouldn’t help prevent her going into DKA. No other precipitating factors were found. She was diagnosed as a case of Catamenial DKA and was started on OCP’s to see how what effect it would have o...

A 25-year-old primi 26 weeks pregnant was admitted with B/L flank pain & pleuritic sounding chest pain. She was septic on initial assessment by the Obstetric team and preliminary investigations revealed high inflammatory markers, raised CRP of 336 & deranged LFT’s. Her USS scan suggested possible hepatitis/cholangitis and blood cultures grew E. coli & she was started on IV Ceftriaxone & metronidazole for the same. At day 3 of her admission, she started det...

Hypothyroidism is a common endocrine condition and if untreated can have serious consequences in pregnant women. Generally, TSH receptor antibodies (TRAb) is performed in hyperthyroid pregnant women as high titres can cause foetal hyperthyroidism Neonatal thyrotoxicosis develops in 1% of infants born to thyrotoxic mothers due to placental transfer of TRAb.As part of management of hypothyroid pregnant women, TRAb are checked routinely in our hospital in k...

Background: Primary Hyperparathyroidism (PHPT) is the leading cause of hypercalcaemia. Early diagnosis and management is important to prevent long term complications. National institute of clinical excellence (NICE) published guidelines on diagnosis and management of Primary Hyperparathyroidism and we sought to compare our practice with the NICE guideline (NG 132).Methods: This was a retrospective observational study of ...

Introduction: The most common sellar and suprasellar lesions are pituitary adenomas, craniopharyngiomas and benign cysts. Rathke’s cleft cyst (RCC) is a benign developmental sellar or suprasellar cystic lesion, which is rarely symptomatic.Case HistoryWe present the case history of 21-year-old woman with a suprasellar RCC, causing early optic chiasmal compression and associated with hyperprolactinemia. Past medical history included neurofibromatosis type 1...

Background: Joint British Diabetes Societies (JBDS) have developed guidelines for the treatment and management of diabetic ketoacidosis (DKA) in adults in the United Kingdom (UK). Multiple single center audits are known to assess compliance to guidelines. However, unified data on DKA management across multiple centers is unknown.Aims: To study the precipitating factors and assess for differences in DKA management across UK hospitals.<p class="abstext...

Introduction: Joint British Diabetes Societies Inpatient (JBDS-IP) recommended reducing fixed-rate intravenous insulin infusion (FRIII) rate to 0.05units/kg/hr when blood glucose falls <14 mmol/l to avoid hypoglycaemia during diabetes-related ketoacidosis (DKA).Aim: We studied the impact of guideline change on complications and outcomes of DKA.Methods: We included all DKA episo...